According to Cas Abbé on Twitter, the most crucial Ethereum trading levels are $2,225, $2,296, $1,994, and $1,222, which represent the average buying prices of wallets holding between 100 to over 100,000 ETH. These levels serve as important support and resistance zones for traders, indicating where large holders are likely to react, increasing the chances of significant price movement around these points (Source: Cas Abbé, Twitter, May 16, 2025). These insights offer valuable guidance for crypto traders seeking to optimize entry and exit points for ETH, especially as large wallet activity often signals institutional sentiment shifts.